HomePortalCalendarGalleryFAQRegisterLog in
Please beware, to register at venomland you are requested to use your full name (first and family name) - nicknames are not allowed and will be not activated! thx

Dear Venomland Members and Friends, Venomland is a little more than 6 years old now and by far the biggest Hot Snake community on the Planet! We want to thank all of you who made Venomland the leading Board. We are also very thankful to our Moderators and Admins for years of hard work. Now, it is time to move on. I have been thinking how to proceed and what to do with our beloved board as we reach a size, that we need to make drastic changes to secure the future of our community. As of now, Venomland is hosted by a free (well mostly free) hosting service. That was good for the first years but now we need to find a new way to run our forum. I have spend hundreds of Dollars over the years to keep Venomland up and running, and i have done so with pleasure. Now, we need your help! We need to come up with several thousand dollars for our Venomland 2.0 project, which i frankly cant pay for any longer by myself. So Venomland is asking his Friends and Members for the first time for their financial Support. Please help to keep Venomland alive, and let us move on to a new, better Portal in the Future! Every Dollar is helping us a great deal. I know, its hard times for everyone, but please spare a few Dollar for our community. If you have only 10 Dollars to spare, we are grateful, if it is more, it would be awesome. We are planning to develop a very new Venomland, with real community functions, a forum like you are already loving it and a real (online) Hot Snake Magazin. Also, there will be download areas for scientific papers, Wallpapers and more. Again folks, we can only do that if you all help. Please send me a Private Message if you want to keep Venomland alive, i will provide you with the details on how to donate Money. For now, we can accept money from creditcards via skrill (please google it, its a free service - account-details will be forwarded to you) and paypal. All the best, and for a (hopefully) nice future of our Board. Mario

Share | 

 Worm gene offers clues to nerve cell repair: study

Go down 
Mario Lutz
Lord of the Serpents
Lord of the Serpents
Mario Lutz

Number of posts : 1416
Age : 51
Location : Puerto Galera, Philippines
Points : 6285
Registration date : 2008-03-06

PostSubject: Worm gene offers clues to nerve cell repair: study   Sat 24 Jan - 12:42

CHICAGO, Jan. 22, 2009 (Reuters) Researchers believe they have found a potential way to regenerate nerves by stimulating a gene and said on Thursday they hope their work in worms may some day help people with spinal cord injuries.

The gene is part of a network, or pathway, of four genes that appear to be essential for nerve repair, they reported in the journal Science.

"We found a pathway that not only regenerates nerves in the worm, but also exists in humans, and we think it serves the same purpose," Michael Bastiani of the University of Utah in Salt Lake City, who led the study, said in a statement.

Bastiani said the gene could serve as a target for a future drug that could "vastly improve the ability of a neuron to regenerate after injury."

In humans, nerve fibers in the arms and legs can regenerate, but in the brain and spinal cord, they do not. Many teams are working to understand why.

Bastiani's team looked to nematode worms for clues. Using an advanced research technique called RNA interference, the team systematically blocked the action of 5,000 worm genes to isolate those important for nerve repair.

They found a gene called dlk-1 was essential to the process at every stage of the worm's life.

When they used genetic engineering to block this gene network, the worms were unable to repair nerve damage.

But when they stimulated the gene -- making it more active than normal -- worms with damaged nerves recovered much more quickly.

Curiously, this network of genes is not used by the nervous system during normal development in the embryo, but it is essential for nerve repair after birth. "Most of us believed that virtually everything we found in regeneration also would be involved in development," Bastiani said.

Bastiani and colleagues noted that to be effective, the dlk-1 gene must be stimulated soon after injury to make a protein that stimulates repair, suggesting there might be "a time window in which you have to activate this pathway."

Many teams have been working on finding ways to block proteins that inhibit nerve repair in adults.

Last year, a team at Children's Hospital Boston reported in the journal Science they were able to stimulate nerve regeneration in mice with damaged optic nerves by turning off proteins that keep adult nerve cells from growing.

A separate team from the biotechnology firm Genentech Inc was able to stimulate nerve regeneration by blocking chemical signals that create a hostile environment for nerve repair.

(Editing by Maggie Fox; Editing by Cynthia Osterman)

well, i just hope it will work one day!

Attitude, rather than disposition is more definitive of serpent behavior. From the moment they emerge into this world until they complete their life cycle, their attitude is "Don't tread on me. I am well equipped to defend myself, but content to pass through life unnoticed. I mean no harm to anything or anyone that our creator has not provided as my bill of fare; I am self sustaining and I like it that way, please pass me by." - W.E. Haast
Back to top Go down
Worm gene offers clues to nerve cell repair: study
Back to top 
Page 1 of 1
 Similar topics
» Worm Tube for the SFG
» Can I use worm vermicast as one of the compost materials?
» Discovery/RRC and also some defender repair panels
» easyjet offers
» Where would you take your RV for repair?

Permissions in this forum:You cannot reply to topics in this forum
VenomLand :: Off Topic :: General Discussions-
Jump to: